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KMID : 0385920210320010019
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Journal of the Korean Society of Emergency Medicine
2021 Volume.32 No. 1 p.19 ~ p.26
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Correlation between hs-CRP and CRP velocity and in-hospital short term prognosis in acute myocardial infarction, which arrived in the ER within 6 hours after symptoms are expressed
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Park Jin-Won
Cho Tae-Jin
Kwak Sae-Jeung
Yun Sung-Hyun
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Abstract
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Objective: This study is to measure the high sensitivity C-reactive protein (hs-CRP) value in acute myocardial infarction (AMI) patients who arrive within 6 hours of the symptom manifestation and see how the resulting value affects the short term prognosis in AMI patients.
Methods: This study was conducted on 118 patients who had less than 6 hours of onset-to-door time among 149 patients who were diagnosed with myocardial infarction in emergency room and undergo percutaneous coronary intervention (PCI) for 2 years from September 2017. The group including main adverse cardiovascular outcomes were compared in the patients according to the blood test figures (hs-CRP on admission [CRP1], CRP velocity [CRPv], post-PCI hs-CRP [CRP2], and CRP difference values [CRP2-1]).
Results: In this study, the average of the hs-CRP values of AMI patients arriving within 6 hours of the symptom manifestation was 2.2±2.3 mg/L. CRP velocity that corrected the CRP value to the elapsed time after the onset of symptoms and N-terminal probrain natriuretic peptide (NT-proBNP) appeared to be significantly correlated with the occurrence of main adverse cardiovascular outcomes (P=0.03).
Conclusion: The hs-CRP values of AMI patients arrived within 6 hours of the symptom manifestation showed the mean risk group. CRPv and NT-proBNP showed a significant casual relationship with main adverse cardiovascular outcomes.
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KEYWORD
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hs-CRP, Velocity, Acute myocardial infarction
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